Abductor Pollicis Longus: Anatomy, Function & Radial Wrist Pain

The Abductor Pollicis Longus (APL) is a deep posterior forearm muscle that plays a major role in thumb positioning and radial-side wrist stability. While it’s often discussed in the context of De Quervain’s tenosynovitis, APL is more than just a pain generator — it’s a key contributor to functional thumb movement.

This page breaks down the anatomy, function, innervation, and clinical relevance of APL.

Watch the Video

Abductor Pollicis Longus – Anatomy Breakdown video here.

Quick Summary

  • Location: Deep posterior forearm, radial side

  • Primary Role: Thumb abduction at the CMC joint

  • Secondary Role: Assists wrist radial deviation

  • Innervation: Posterior interosseous nerve (radial nerve branch)

Anatomy at a Glance

Origin:

  • Posterior surface of the ulna

  • Posterior surface of the radius

  • Interosseous membrane

Pathway & Compartment:
APL travels distally along the radial side of the posterior forearm and passes beneath the extensor retinaculum in the 1st dorsal compartment, alongside Extensor Pollicis Brevis (EPB).

This tight compartment is clinically important and commonly implicated in radial wrist pain.

Insertion:

  • Base of the 1st metacarpal

  • Occasionally sends slips to the trapezium (anatomical variation is common)

What It Actually Does

Primary Function:

  • Abducts the thumb at the carpometacarpal (CMC) joint

Secondary Contributions:

  • Assists with wrist radial deviation

  • Helps position the thumb for grip, pinch, and precision tasks

APL doesn’t just move the thumb — it sets the thumb up to work efficiently with the rest of the hand.

Why This Matters Clinically

APL is one of the most frequently discussed thumb muscles in rehab settings.

✔️ Radial-side wrist pain

  • APL is commonly involved in De Quervain’s tenosynovitis, especially with repetitive thumb motion.

✔️ Pain with gripping or lifting

  • Particularly when the thumb is abducted under load (lifting a phone, kettlebell, or child).

✔️ Thumb control issues

  • Poor APL function can affect CMC joint mechanics and overload nearby tissues.

Because APL shares a tight compartment with EPB, irritation often reflects load tolerance issues, not just inflammation.

Practical Insight for Training & Rehab

  1. Thumb abduction with control

    • Light resistance, slow range, emphasis on smooth motion.

  2. CMC positioning before strength

    • Teaching proper thumb alignment reduces unnecessary stress.

  3. Grip without over-abduction

    • Excessive thumb flare during lifting can irritate APL over time.

APL responds best to graded loading and movement quality, not aggressive strengthening.

Quick FAQ

What does Abductor Pollicis Longus do?
It abducts the thumb and helps stabilize the radial side of the wrist.

Why is APL linked to De Quervain’s?
Because it shares the tight first dorsal compartment with EPB and is heavily loaded during repetitive thumb use.

Is APL a wrist or thumb muscle?
Primarily a thumb muscle, with secondary effects at the wrist.

Want Better Thumb & Wrist Function?

Thumb pain is rarely random — it’s usually a loading and control issue. Anatomy helps clarify where to focus.

Click here to work with Treadwell, DPT.

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Extensor Pollicis Brevis: Anatomy, Function & Thumb Extension Control

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Supinator: Anatomy, Function & Why Forearm Rotation Matters